DU, YINGFENG
Professor of Department of Pharmaceutical Analysis
Tutor of Pharmaceutical Analysis
School of Pharmacy
Phone: 86-311-86265625
Email: yingfengdu@163.com
Research Summary
Professor Du’s research focuses on the quality control of new drugs, analysis of chemical ingredients of Traditional Chinese Medicine and Chemical Medicine in vivo and application of MS and capillary electrophoresis, with publications in Science of the Total Environment, Toxicology, Journal of Chromatography A, RSC Advances Journal of Separation Science, Analytical Biochemistry, Journal of Pharmaceutical and Biomedical Analysis etc.
Education
2008-2011 Ph.D., Pharmaceutical Analysis, Hebei Medical University
2001-2004 M.S., Pharmaceutical Analysis, Hebei Medical University
1994-1998 B.S., Department of Pharmacy, Hebei Medical University
Academic Experience
2016 -Professor of Pharmaceutical Analysis, Hebei Medical University
2011- Vice Professor of Pharmaceutical Analysis, Hebei Medical University
Awards and Honors
1. The Second Prize of Hebei Province Science and Technology Progress Award. The first person to complete (2015JB2045-1)
2. The First Prize of Science and Technology of Hebei Society of Traditional Chinese Medicine. The first person to complete (20141001)
Funding project:
1. The National Natural Science Foundation（2015,No: 81402894）,Project manager
2. The Hebei Natural Science Foundation（2019, H2019206560），Project manager
3. The Key Project of Hebei Provincial Department of Education(2017, ZD2017244）,Project manager

Publications
Papers and Articles
1. Characterization of serum metabolites as biomarkers of carbon black nanoparticles-induced subchronic toxicity in rats by hybrid triple quadrupole time-of-flight mass spectrometry with non-targeted metabolomics strategy. Toxicology, 2019,426, 152268. 2019.11. IF 4.099. First author
2. Metabolites identification of (+)-usnic acid in vivo by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Fitoterapia, 2019,13, 85-95. 2019.10.IF 2.527. Corresponding Author
3.Cell metabomics to study the cytotoxicity of carbon black nanoprticles on A549 cells using UHPLC-Q/TOF-MS and multivariate data analysis. Science of the Total Environment, 2020, 698, 134122. 2020.2. IF 6.551. Corresponding Author
4. A novel strategy for the characterization of glaucocalxin A metabolites in vivo and in vitro by UHPLC-Q-TOF-MS based on DDA and DIA data acquisitions. RSC Advances, 2020, 10, 10431. 2020.4. IF 3.119. Corresponding Author
5. Chemical profiling and total quality assessment of Isodon japonica using data-independent acquisition mode combined with superimposed multiple product ion UHPLC-Q-TOF-MS and chemometric analysis. RSC Adv, 2019, 9, 1403-1418. IF 3.119. Corresponding Author
7. UHPLC-Q-TOF-MS/MS-oriented characteristic components dataset and multivariate statistical techniques for the holistic quality control of Usnea RSC Adv, 2018, 8, 15487-15550. Corresponding Author 
8. A practical strategy for the characterization   of ponicidin metabolites in vivo and in vitro  by UHPLC-Q-TOF-MS based on nontargeted SWATH data acquisition Journal of Pharmaceutical and Biomedical Analysis,2017,145,865-878. Corresponding Author
9. Identification and comparative oridonin metabolism in different species liver microsomes by using UPLC-Triple-TOF-MS/MS and PCA. Analytical Biochemistry, 2016, 511: 61-73. Corresponding Author
10. Differentiation of Isodon japonica and Adulterants Based on Identification andQuantitation 14 Diterpenoids Using LC-MS-MS Library Search Approach and Hierarchical Cluster Analysis. Journal of Chromatographic Science, 2016, 54 (3):367-376. Corresponding Author
11. Simultaneous Quantification of 11 Constituents in Wuji Pill Using Ultra Performance Liquid Chromatography Coupled With a Triple Quadrupole Electrospray Tandem Mass Spectrometry. Journal of Chromatographic Science, 2016, 54 (2):237-245. Corresponding Author
12. Simultaneous determination of ginsenoside Rb1, naringin, ginsenosideRb2and oridonin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study after oral administration of Weifuchun tablet. Journal of Chromatography B, 2015,1000:112-119. Corresponding Author
 13. Identification of metabolites of oridonin in rats with a single run on UPLC-Triple-TOF-MS/MS system based on multiple mass defect filter data acquisition and multiple data processing techniques. Journal of Chromatography B, 2015,1006:80-92. Corresponding Author 
14. Quantitative analysis of ten diterpenoids in rat bile after oral administration of Isodon rubescens extract by high performance liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of Liquid Chromatography & Related Technologies, 2013, 36, 1264-1279. First Author
15. A sensitive analysis method for 7 diterpenoids in rat plasma by liquid chromatography?Celectrospray ionization mass spectrometry and its application to pharmacokinetic study of Isodon serra extract. Journal of Chromatography A, 2011, 1218:7771-7780. First Author
16. A novel analysis method for diterpenoids in rat plasma by liquid chromatography-electrospray ionization mass spectrometry. Analytical Biochemistry, 2010,407:111-119. First Author
17. Simultaneous qualitative and quantitative analysis of 28 components in Isodon rubescens by HPLC-ESI-MS/MS. Journal of Separation Science, 2010,33:545-557. First Author
18. Rapid method for simultaneous determination of 20 components in Isodon nervosa by high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry. Phytochemical Analysis, 2010,21,416-427. First Author