Meng Li

Information

Professor, Supervisor of Doctorate Candidates, Supervisor of Master's Candidates

Laboratory of Inorganic and Physicochemistry, 

School of Pharmaceutical Sciences. 

E-mail: limeng87@hotmail.com

Work Experience

2018-present  Professor, Hebei Medical University. 

2015-2017  Postdoctoral Fellow, Wayne State University, USA. 

Education

2009-2015  Ph.D. Inorganic Chemistry, Changchun Institute of Applied Chemistry , Chinese Academy of Sciences, China. 

2005-2009  B.S. Applied Chemistry, Huazhong University of Science and Technology, China. 

Research Interests

1.Engineering multifunctional inorganic nanomaterials for the diagnosis and treatment of cancer and Alzheimer’s disease.

2.Engineering synthetic nanomaterials as antigen/adjuvant or drug carriers for subunit vaccine delivery.

3.Catalytic mechanism of nanozyme and its potential biological application.

External Funds (As Principal Investigator) 

1.National Natural Science Foundation of China (2019-2021), Grant No: 21807024, Selective recognition of β-Amyloid peptide and modulation of its aggregation behavior by chiral nanoparticles.

2.Hebei Youth Top Talent Support Program (2018.07-2021.06).

3."100 Talents Plan" of Hebei Province (2019.02-2022.01).

4.Youth Top Talent Project of Hebei Province Higher Education (2018.04-2020.12), Grant No: BJ2018007.

Awards

1.Youth Science and Technology Award Winner of Hebei Province

2.The third-level Talent for the “Three-Three-Three Talent Project” in Hebei Province

3.Top Talent of Young People of Hebei Province

4.Chinese Academy of Sciences Dean Awarding

Representative publications

At present, more than 40 papers have been published, which are all indexed by SCI or SSCI. Prof. Li is the first or correspondent author on 24 SCI/SSCI papers. As the first author or correspondent, she published 1 paper on Advanced Materials, 1 paper on Journal of the American Chemical Society, 4 papers on Chemical Science. Her one paper was selected as ESI High cited paper. Mainly include:

1.Meng Li, Zhenqi Liu, Jinsong Ren, Xiaogang Qu. Molecular crowding effects on the biochemical properties of amyloid β-heme, Aβ-Cu and Aβ-heme-Cu complexes. Chemical Science 2020, 11, 7479-7486.

2.Cong Zhang, Min Cui, Jujie Ren, Yifei Xing, Na Li, Haiyan Zhao, Peng Liu, Xueping Ji, Meng Li*. Facile synthesis of novel spherical covalent organic frameworks integrated with Pt nanoparticles and multiwalled carbon nanotubes as electrochemical probe for tanshinol drug detection. Chemical Engineering Journal 2020, 401, 126025

3.Meng Li, Jie Lv, Shuangling Wang, Jing Wang, Yulong Lin. Expanded mesoporous silica-encapsulated ultrasmall Pt nanoclusters as artificial enzymes for tracking hydrogen peroxide secretion from live cells. Analytica Chimica Acta 2020, 1104, 180-187.

4.Yulong Lin, Yalin Wang, Jie Lv, Nannan Wang, Jing Wang, Meng Li*. Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity. International journal of nanomedicine 2019, 14, 5817. 

5.Shuangling Wang, Han Yan, Yalin Wang, Na Wang, Yulong Lin, Meng Li*. Hollow Prussian Blue nanocubes as peroxidase mimetic and enzyme carriers for colorimetric determination of ethanol. Mikrochimica Acta 2019, 186, 738.

6.Meng Li, Yijia Guan, Andong Zhao, Jinsong Ren, Xiaogang Qu. Using Multifunctional Peptide Conjugated Au Nanorods for Monitoring β-amyloid Aggregation and Chemo-Photothermal Treatment of Alzheimer's Disease. Theranostics 2017, 7, 2996-3006. 

7.Meng Li, Yijia Guan, Zhaowei Chen, Nan Gao, Jinsong Ren, Kai Dong, Xiaogang Qu. Platinum-coordinated graphitic carbon nitride nanosheet used for targeted inhibition of amyloid β-peptide aggregation. Nano Research 2016, 9, 2411-2423. 

8.Meng Li, Chuanqi Zhao, Jinsong Ren, Xiaogang Qu. Chiral Metallo-Supramolecular Complex Directed Enantioselective Self-Assembly of β-Sheet Breaker Peptide for Amyloid Inhibition. Small 2015, 11, 4651-4655. 

9.Meng Li, Suzanne E. Howson, Kai Dong, Nan Gao, Jinsong Ren, Peter Scott, Xiaogang Qu. Chiral Metallohelical Complexes Enantioselectively Target Amyloid β for Treating Alzheimer’s Disease. Journal of the American Chemical Society 2014, 136, 11655-11663. 

10.Meng Li, Peng Shi, Can Xu, Jinsong Ren, Xiaogang Qu. Cerium oxide caged metal chelator: anti-aggregation and anti-oxidation integrated H2O2-responsive controlled drug release for potential Alzheimer’s disease treatment. Chemical Science 2013, 4, 2536-2542.

11.Meng Li, Xinjian Yang, Jinsong Ren, Konggang Qu, Xiaogang Qu. Using Graphene Oxide High Near-Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease. Advanced Materials 2012, 24, 1722-1728.