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药剂学

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李蒙博士-教授

发布时间:2020-11-10   浏览次数:0

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李蒙,女,1987年8月出生,教授,现就职于皇冠hg1088官方官网无机物化教研室。担任学术团体职务包括:河北省毒理学会理事,河北省侨联侨界专家委员会委员。2015年博士毕业于中国科学院长春应用化学研究所获理学博士学位,2015-2017年在美国Wayne State University进行了为期两年的博士后研究工作。近年来主持国家自然科学基金、河北省“百人计划”项目、河北省青年拔尖人才支持计划等项目,作为学术骨干成员参与河北省自然科学基金创新研究群体项目。目前已发表SCI论文60余篇,授权专利3项。其中以第一作者或通讯作者发表高水平学术论文40篇,包括顶级期刊Journal of the American Chemical Society, Advanced Materials, Chemical Engineering Journal等。入选河北省政府特殊津贴专家,河北省“百人计划”人选,河北省“三三三人才工程”第三层次人选。获河北省青年拔尖人才称号,第十四届河北省青年科技奖。现专注于生物功能纳米材料的构建及其在疾病诊断与治疗中的应用研究,包括肿瘤微环境响应性纳米智能药物载体的构建和生物功能材料调控蛋白构象及抗阿尔茨海默症性能研究等。

近期代表性论文

1.Shuyang Hu, Xinlu Ning, Jie Lv, Yuxin Wei, Huiran Zhang*, Meng Li*. Enantioselective modulation of amyloid burden and memory deficits by chiral polyoxometalates for Alzheimer's disease treatment. Inorganic Chemistry Frontiers 2023, 10, 5347-5356.

2.Yu Pang, Jie Lv, Chengcai He, Chengda Ju, Yulong Lin, Cong Zhang*, Meng Li*. Covalent organic frameworks-derived carbon nanospheres based nanoplatform for tumor specific synergistic therapy via oxidative stress amplification and calcium overload. Journal of Colloid and Interface Science 2024, 661, 908-922.

3.Shuangling Wang, Yu Pang, Shuyang Hu, Jie Lv, Yulong Lin, Meng Li*. Copper sulfide engineered covalent organic frameworks for pH-responsive chemo/photothermal/chemodynamic synergistic therapy against cancer. Chemical Engineering Journal 2023, 451, 138864.

4.Jie Lv, Xiaoyu Wang, Xue Zhang, Runpei Xu, Shuyang Hu, Shuangling Wang, Meng Li*. Tumor microenvironment-responsive artesunate loaded Z-scheme heterostructures for synergistic photo-chemodynamic therapy of hypoxic tumor. Asian Journal of Pharmaceutical Sciences 2023, 18, 100798.

5.Jie Lv, Shuangling Wang, Duo Qiao, Yulong Lin, Shuyang Hu, Meng Li*. Mitochondria-targeting multifunctional nanoplatform for cascade phototherapy and hypoxia-activated chemotherapy. Journal of Nanobiotechnology 2022, 20, 42. 

6.Shuangling Wang, Jie Lv, Yu Pang, Shuyang Hu, Yulong Lin, Meng Li*. Ion channel-targeting near-infrared photothermal switch with synergistic effect for specific cancer therapy. Journal of Materials Chemistry B 2022, 10, 748-756. 

7.Yana Chen, Shuangling Wang, Jujie Ren, Haiyan Zhao, Min Cui, Na Li, Meng Li*, Cong Zhang*. Electrocatalysis of Copper Sulfide Nanoparticle-Engineered Covalent Organic Frameworks for Ratiometric Electrochemical Detection of Amyloid‑β Oligomer. Analytical Chemistry, 2022, 94, 11201-11208.

8.Xi Zhou, Shuyang Hu, Shuangling Wang, Yu Pang, Yulong Lin, Meng Li*. Large amino acid mimicking selenium-doped carbon quantum dots for multi-target therapy of Alzheimer's disease. Frontiers in Pharmacology 2021, 12, 778613. 

9.Xi Zhou, Shuangling Wang, Cong Zhang*, Yulong Lin, Jie Lv, Shuyang Hu, Shanshan Zhang, Meng Li*. Colorimetric determination of amyloid-β peptide using MOF-derived nanozyme based on porous ZnO-Co3O4 nanocages. Microchimica Acta 2021, 188, 56. 

10.Jie Lv, Cong Zhang, Shuangling Wang, Meng Li*, Wei Guo*. MOF-derived porous ZnO-Co3O4 nanocages as peroxidase mimics for colorimetric detection of copper (II) ions in serum. Analyst 2021, 146, 605-611.

11.Meng Li, Arata Itoh, Jingchao Xi, Chunsong Yu, Yuehong Wu, William M. Ridgway, Haipeng Liu*. Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides. The Journal of Immunology 2021, 207, 2051-2059.

12.Meng Li, Zhenqi Liu, Jinsong Ren, Xiaogang Qu*. Molecular crowding effects on the biochemical properties of amyloid β-heme, Aβ-Cu and Aβ-heme-Cu complexes. Chemical Science 2020, 11, 7479-7486.

13.Cong Zhang, Min Cui, Jujie Ren*, Yifei Xing, Na Li, Haiyan Zhao, Peng Liu, Xueping Ji, Meng Li*. Facile synthesis of novel spherical covalent organic frameworks integrated with Pt nanoparticles and multiwalled carbon nanotubes as electrochemical probe for tanshinol drug detection. Chemical Engineering Journal 2020, 401, 126025. 

14.Cong Zhang, Jujie Ren*, Yifei Xing, Min Cui, Na Li, Peng Liu, Xiaofang Wen, Meng Li*. Fabrication of hollow ZnO-Co3O4 nanocomposite derived from bimetallic-organic frameworks capped with Pd nanoparticles and MWCNTs for highly sensitive detection of tanshinol drug. Materials Science and Engineering: C 2020, 108, 110214. 

15.Jie Lv#, Shuangling Wang#, Cong Zhang*, Yulong Lin, Yan Fu, Meng Li*. ATP induced alteration in the peroxidase-like properties of hollow Prussian blue nanocubes: a platform for alkaline phosphatase detection. Analyst 2020, 145, 5032-5040. 

16.Meng Li#, Jie Lv#, Shuangling Wang, Jing Wang*, Yulong Lin*. Expanded mesoporous silica-encapsulated ultrasmall Pt nanoclusters as artificial enzymes for tracking hydrogen peroxide secretion from live cells. Analytica Chimica Acta 2020, 1104, 180-187. 

 


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